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Real members of MyDesmoidTumorTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
September 27, 2025
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A MyDesmoidTumorTeam Member

Yes, nausea is common. Ovary toxicity too. And dehydration, you need to drink tons of water! If it upsets the digestive system too much, ask them if it's possible to adapt the dose, but sometimes it happens until your body gets used to it, then it's smooth sailing with a lot of water intake 🩵

October 29, 2025
A MyDesmoidTumorTeam Member

Thankyou also discovered that diet is a key factor as well i have had to reduce diary redmeat and some green vegetables i have just started to introduce them back slowly into my daily meals as i was having bad reflux.

January 16
MyDesmoidTumorTeam

Yes, nausea is a known side effect of Ogsiveo (nirogacestat), which is a targeted therapy used to treat desmoid tumors. While some people may start treatment with minimal symptoms, side effects can develop over time.

Here are some ways to manage treatment-related nausea
• Keep a symptom log to track when nausea occurs
• Eat Show Full Answer

Yes, nausea is a known side effect of Ogsiveo (nirogacestat), which is a targeted therapy used to treat desmoid tumors. While some people may start treatment with minimal symptoms, side effects can develop over time.

Here are some ways to manage treatment-related nausea:
• Keep a symptom log to track when nausea occurs
• Eat small, frequent meals
• Stay well hydrated
• Try natural remedies like ginger
• Avoid strong odors
• Keep your environment cool If you're experiencing increasing nausea, don't hesitate to contact your healthcare team. They can prescribe anti-nausea medications (antiemetics) like ondansetron (Zofran) or prochlorperazine (Compazine) to help control your symptoms. If one anti-nausea medication isn't working well enough, your doctor can recommend alternative options.

Contact your doctor immediately if you:
• Can't keep fluids down
• Are unable to take your medications
• Experience significant weight loss
• Have severe pain
• Develop a fever

September 27, 2025

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