MyDesmoidTumorTeam

Are there any new medications for a desmoid tumor in the jaw, especially since your daughter's tumor grew during her last pregnancy?

Yes, there is a new medication specifically approved for desmoid tumors. In November 2023, the FDA approved nirogacestat (Ogsiveo) as the first medication specifically for desmoid tumors. This Show Full Answer

Are there any new medications for a desmoid tumor in the jaw, especially since your daughter's tumor grew during her last pregnancy?

Yes, there is a new medication specifically approved for desmoid tumors. In November 2023, the FDA approved nirogacestat (Ogsiveo) as the first medication specifically for desmoid tumors. This targeted therapy blocks a protein called gamma-secretase that desmoid tumor cells use to grow and divide.

Other medication options that may be used include:
* Tyrosine kinase inhibitors (TKIs) like imatinib (Gleevec), pazopanib (Votrient), and sorafenib (Nexavar) - these are used off-label
* Chemotherapy, which can help shrink or control tumor growth
* Radiation therapy for tumors that don't respond to other treatments

Regarding pregnancy-related growth, desmoid tumors can be influenced by hormones like estrogen, which may explain why your daughter's tumor grew during pregnancy. For future pregnancies, active surveillance is usually the preferred approach since many systemic medications aren't appropriate during pregnancy due to potential harm to the fetus.

It's important for your daughter to work closely with both her obstetrics team and desmoid tumor specialists to determine the best treatment plan, especially if she's considering future pregnancies or is currently breastfeeding.

 AI-generated responses are not a substitute for medical advice. These services are not intended to diagnose, treat, or cure any condition or disease. Always ask your doctor about specific health concerns.

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