Does nirogacestat (Ogsiveo) cause hair loss?
Yes, hair loss is a known side effect of nirogacestat. In clinical trials, hair loss occurred in more than 15 percent of people taking the medication.
While hair loss can be concerning, most side effects reported in the clinical trials weren't considered severe. About 95 percent of Show Full Answer
Does nirogacestat (Ogsiveo) cause hair loss?
Yes, hair loss is a known side effect of nirogacestat. In clinical trials, hair loss occurred in more than 15 percent of people taking the medication.
While hair loss can be concerning, most side effects reported in the clinical trials weren't considered severe. About 95 percent of side effects were manageable.
If you're experiencing hair loss or other side effects while taking nirogacestat, it's important to discuss this with your healthcare team. They can help you understand what to expect and provide guidance on managing this side effect.
December 12, 2025